WebOur scientific team has established standard procedures for the differentiation of iPSC lines into multiple cell types in the cardiovascular and neurological lineages that can be supplied at scale large enough for modeling, assay development and screening. Neural Astrocytes. Human iPSC-derived astrocytes. Cardiac Atrial Cardiomyocytes. WebApr 12, 2024 · Dr Bhagwan completed a PhD and postdoc at The University of Nottingham in the laboratory of Prof Chris Denning, using human iPSC-derived cardiomyocytes and CRISPR Cas9 to model hypertrophic cardiomyopathy in vitro and identify potential therapeutic interventions. At Axol Bioscience Ltd., Jamie is a scientific Group Leader, primarily …
Subtype-Directed Differentiation of Human iPSCs into Atrial and ...
WebAug 16, 2024 · During the past decade, induced pluripotent stem cell–derived cardiomyocytes (iPSC-CMs) have emerged as one of the most important tools in the field … WebOct 15, 2024 · Meanwhile, patient-specific cardiomyocytes derived from autologous induced pluripotent stem cells (iPSCs) could become the major exogenous sources for replenishing the damaged myocardium. Human iPSC-derived cardiomyocytes (iPSC-CMs) are relatively immature and have the potential to increase the population of cells that advance to … shareafter
Rajneesh Jha, Ph.D. - Associate Principal Scientist
WebJan 19, 2024 · Human induced pluripotent stem cells (iPSCs) present a renewable supply of otherwise difficult to obtain human cell types, particularly in the study of cardiac [ 2 ], neurological [ 3 ], and metabolic diseases, showing great potential for drug development/screening, gene therapy, and regenerative medicine. WebJan 12, 2024 · Induced pluripotent stem cells (iPSCs) offer an unprece-dented opportunity to study human physiology and disease at the cellular level. They also have the potential to be leveraged in the practice of ... large numbers and differentiated into a variety of cell types that are relevant to cardiovascular diseases—including cardiomyocytes, ... Web1.Ability to be produced from anyone’s cells. iPSCs are made by introducing four special factors into various types of cells such as blood, skin, and hair cells, and culturing them. With current technology, iPSCs can be made with just 5 mL of blood. 2. Ability to be transformed into cells of various tissues and organs. pool floats with back support